I thought there was a limit of litters with some of the organizations (TICA, Cat Fancier's Association, GCCF), but I'm not finding that information and many state there is no limit. However, if I were a breeder, I would limit a queen to no more than two litters per year. That allows her two months for the pregnancy, two months to nurse and wean her kitties. And two months to recuperate before breeding again. In fact, I would probably limit to one litter per year. My concern would be more for the mother and kittens and not about how many kittens I can sell in a year. A younger queen may do okay with two per year, but the older they get, the harder it is and most queens are retired after 3 to 4 years. You just can't wear them out having and caring for kittens. I'm sure there are some breeders who overbreed their queens.
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