Welcome to our forum. I am genuinely surprised that you've had several years of your baby sleeping through the night and he is just now starting to wake you up. Mine gets me up at least twice during the night every single night. I would love for him to at least wait until 5:30 a.m.
First of all, let me tell you that heart murmurs are very common in bengals, due to the heavy imbreeding that continues to go on to this day. I have researched over 50,000 cats and am amazed at the number of parents that are also the grandparents. A low-grade heart murmur is not really anything to worry about. Mine has a grade 3 and is fine.
As to what you can do to keep your boy sleeping longer? Does he get to eat before you go to bed? Mine is a grazer and eats about every two hours. He isn't into dry food, which is out 24/7 for our other cat, so I do have to get up and make sure he gets some wet food to satisfy him.
You might try playing heavily with him before you go to bed and tire him out a little more. If nothing has changed in his environment, then it may be the fact that the days are getting shorter (unless you are in Australia or New Zealand) and when the sun comes up -- the cat wakes up.
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